Mission Valley is positively in the middle of it all. There's no shortage of ways to reach this central neighborhood. From the north or south Interstate 5, exit to I-8 westbound. Several exits along the highway will take you to hotel circle, Fashion Valley Mall, and Mission Valley Shopping Center. Interstate 805 and 15 connect to I-8 as well. Just head west when connecting and exit along hotel circle. State highway 163 passes directly through Mission Valley - exit on Friars road; head west or east and you'll be sure to hit a shopping mall!